The role of apolipoprotein N‐acyl transferase, Lnt, in the lipidation of factor H binding protein of Neisseria meningitidis strain MC58 and its potential as a drug target

BACKGROUND AND PURPOSE: The level of cell surface expression of the meningococcal vaccine antigen, Factor H binding protein (FHbp) varies between and within strains and this limits the breadth of strains that can be targeted by FHbp‐based vaccines. The molecular pathway controlling expression of FHb...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: da Silva, R A G, Churchward, C P, Karlyshev, A V, Eleftheriadou, O, Snabaitis, A K, Longman, M R, Ryan, A, Griffin, R
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Themed Section: Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481643/
https://ncbi.nlm.nih.gov/pubmed/27784136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13660
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