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Ca(2+) Dependent Surface Trafficking of Norepinephrine Transporters Depends on Threonine 30 and Ca(2+) Calmodulin Kinases

The antidepressant-sensitive norepinephrine (NE) transporter (NET) inactivates NE released during central and peripheral neuronal activity by transport into presynaptic cells. Altered NE clearance due to dysfunction of NET has been associated with the development of mental illness and cardiovascular...

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Pubblicato in:J Chem Neuroanat
Autori principali: Sung, Uhna, Binda, Francesca, Savchenko, Valentina, Owens, William A., Daws, Lynette C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481502/
https://ncbi.nlm.nih.gov/pubmed/28017803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchemneu.2016.12.003
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