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Prevention of long-term memory loss after retrieval by an endogenous CaMKII inhibitor
CaMK2N1 and CaMK2N2 are endogenous inhibitors of calcium/calmodulin-dependent protein kinase II (CaMKII), a key synaptic signaling molecule for learning and memory. Here, we investigated the learning and memory function of CaMK2N1 by knocking-down its expression in dorsal hippocampus of mice. We fou...
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Publicado no: | Sci Rep |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group UK
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5481336/ https://ncbi.nlm.nih.gov/pubmed/28642476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04355-8 |
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