Single-cell profiling of an in vitro model of human interneuron development reveals temporal dynamics of cell type production and maturation

GABAergic interneurons are essential for neural circuit function and their loss or dysfunction is implicated in human neuropsychiatric disease. In vitro methods for interneuron generation hold promise for studying human cellular and functional properties and ultimately therapeutic cell replacement....

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Publicado no:Neuron
Main Authors: Close, Jennie L., Yao, Zizhen, Levi, Boaz P., Miller, Jeremy A., Bakken, Trygve E., Menon, Vilas, Ting, Jonathan T., Wall, Abigail, Krostag, Anne-Rachel, Thomsen, Elliot R., Nelson, Angel M., Mich, John K., Hodge, Rebecca D., Shehata, Soraya I., Glass, Ian A., Bort, Susan, Shapovalova, Nadiya V., Ngo, N. Kiet, Grimley, Joshua S., Phillips, John W., Thompson, Carol L., Ramanathan, Sharad, Lein, Ed
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480972/
https://ncbi.nlm.nih.gov/pubmed/28279351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.02.014
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