Heart rate lowering treatment leads to a reduction in vulnerable plaque features in atherosclerotic rabbits

OBJECTIVE: To investigate the effect of a heart rate (HR) lowering agent (Ivabradine) on features of atherosclerotic plaque vulnerability with magnetic resonance imaging (MRI), ultrasound imaging, and histology. APPROACH AND RESULTS: Atherosclerosis was induced in the abdominal aorta of 19 rabbits....

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: van Hoof, Raf H. M., Hermeling, Evelien, Sluimer, Judith C., Salzmann, Julie, Hoeks, Arnold P. G., Roussel, Jérôme, Daemen, Mat J. A. P., Struijker-Boudier, Harry, Wildberger, Joachim E., Heeneman, Sylvia, Kooi, M. Eline
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480870/
https://ncbi.nlm.nih.gov/pubmed/28640847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179024
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