High-Throughput Patch Clamp Screening in Human α6-Containing Nicotinic Acetylcholine Receptors

Nicotine, the addictive component of tobacco products, is an agonist at nicotinic acetylcholine receptors (nAChRs) in the brain. The subtypes of nAChR are defined by their α- and β-subunit composition. The α6β2β3 nAChR subtype is expressed in terminals of dopaminergic neurons that project to the nuc...

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Detalhes bibliográficos
Publicado no:SLAS Discov
Main Authors: Armstrong, Lucas C., Kirsch, Glenn E., Fedorov, Nikolai B., Wu, Caiyun, Kuryshev, Yuri A., Sewell, Abby L., Liu, Zhiqi, Motter, Arianne L., Leggett, Carmine S., Orr, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2017
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480602/
https://ncbi.nlm.nih.gov/pubmed/28298165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2472555217696794
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