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Synthesis of tert-butyl (substituted benzamido)phenylcarbamate derivatives: anti-inflammatory activity and docking studies

A series of new tert-butyl 2-(substituted benzamido) phenylcarbamate (4a–4j) were synthesized by the condensation of tert-butyl 2-amino phenylcarbamate (3) with various substituted carboxylic acid in the presence of EDCI and HOBt as coupling reagent, obtain in excellent yields. The structures of all...

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Publicado en:J Chem Biol
Main Authors: Bhookya, Shankar, Pochampally, Jalapathi, Valeru, Anil, Sunitha, Vianala, Balabadra, Saikrishna, Manga, Vijjulatha, Kudle, Karunakar rao
Formato: Artigo
Idioma:Inglês
Publicado: Springer Berlin Heidelberg 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480262/
https://ncbi.nlm.nih.gov/pubmed/28684997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12154-017-0168-x
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