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Deltex Regulates T-Cell Activation by Targeted Degradation of Active MEKK1
Deltex is known as a Notch signal mediator, but its physiological action mechanism is poorly understood. Here we identified a new regulatory role of Deltex in T-cell activation. Deltex expression was constitutive in resting T cells and was reduced upon T-cell receptor (TCR)-stimulated activation. Th...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2005
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC548012/ https://ncbi.nlm.nih.gov/pubmed/15684388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.4.1367-1378.2005 |
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