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Heparin Mimics Extracellular DNA in Binding to Cell Surface-Localized Proteins and Promoting Staphylococcus aureus Biofilm Formation

Staphylococcus aureus is a leading cause of catheter-related bloodstream infections. Biofilms form on these implants and are held together by a matrix composed of proteins, polysaccharides, and extracellular DNA (eDNA). Heparin is a sulfated glycosaminoglycan that is routinely used in central venous...

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Detalhes bibliográficos
Publicado no:mSphere
Main Authors: Mishra, Surabhi, Horswill, Alexander R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5480030/
https://ncbi.nlm.nih.gov/pubmed/28656173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSphere.00135-17
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