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What Else Can CD39 Tell Us?

As the rate-limiting enzyme in ATP/ADP–AMP–adenosine pathway, CD39 would be a novel checkpoint inhibitor target in preventing adenosine-triggered immune-suppressive effect. In addition, CD39(hi) Tregs, but not CD25(hi) Tregs, exhibit sustained Foxp3 levels and functional abilities, indicating it cou...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zhao, Hai, Bo, Cong, Kang, Yan, Li, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479880/
https://ncbi.nlm.nih.gov/pubmed/28690614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00727
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