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Two common human CLDN5 alleles encode different open reading frames but produce one protein isoform
Claudins provide tight junction barrier selectivity. The human CLDN5 gene contains a high-frequency single-nucleotide polymorphism (rs885985), where the G allele encodes for glutamine (Q) and the A allele encodes for an amber stop codon. Thus, these different CLDN5 alleles define nested open reading...
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Publicado no: | Ann N Y Acad Sci |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5479753/ https://ncbi.nlm.nih.gov/pubmed/28445614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.13342 |
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