SensiScreen(®) KRAS exon 2-sensitive simplex and multiplex real-time PCR-based assays for detection of KRAS exon 2 mutations

Activating mutations in codon 12 and codon 13 of the KRAS (Kirsten rat sarcoma viral oncogene homolog) gene are implicated in the development of several human cancer types and influence their clinical evaluation, treatment and prognosis. Numerous different methods for KRAS genotyping are currently a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Riva, Alice, BØrgesen, Michael, Guldmann-Christensen, Mariann, Hauge Kyneb, Majbritt, Voogd, Kirsten, Andersen, Christina, Epistolio, Samantha, Merlo, Elisabetta, Yding Wolff, Tine, Hamilton-Dutoit, Stephen, Lorenzen, Jan, Christensen, Ulf Bech, Frattini, Milo
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479524/
https://ncbi.nlm.nih.gov/pubmed/28636636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0178027
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