Optimization of alginate purification using polyvinylidene difluoride membrane filtration: Effects on immunogenicity and biocompatibility of three-dimensional alginate scaffolds

Sodium alginate is an effective biomaterial for tissue engineering applications. Non-purified alginate is contaminated with protein, lipopolysaccharide, DNA, and RNA, which could elicit adverse immunological reactions. We developed a purification protocol to generate biocompatible alginate based on...

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Bibliografiske detaljer
Udgivet i:J Biomater Appl
Main Authors: Sondermeijer, Hugo P, Witkowski, Piotr, Woodland, David, Seki, Tetsunori, Aangenendt, Frank J, van der Laarse, Arnoud, Itescu, Silviu, Hardy, Mark A
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479495/
https://ncbi.nlm.nih.gov/pubmed/27114440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0885328216645952
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