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Neutral Loss is a Very Common Occurrence in Phosphotyrosine-containing Peptides Labeled with Isobaric Tags

While developing a multiplexed phosphotyrosine peptide quantification assay, an unexpected observation was made – significant neutral loss from phosphotyrosine (pY) containing peptides. Using a 2000-member peptide library, we sought to systematically investigate this observation by comparing unlabel...

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Podrobná bibliografie
Vydáno v:J Proteome Res
Hlavní autoři: Everley, Robert A., Huttlin, Edward L., Erickson, Alison R., Beausoleil, Sean A., Gygi, Steven P.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5479408/
https://ncbi.nlm.nih.gov/pubmed/27978624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jproteome.6b00487
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