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Galectin-3 Is a Target for Proteases Involved in the Virulence of Staphylococcus aureus

Staphylococcus aureus is a major cause of skin and soft tissue infection. The bacterium expresses four major proteases that are emerging as virulence factors: aureolysin (Aur), V8 protease (SspA), staphopain A (ScpA), and staphopain B (SspB). We hypothesized that human galectin-3, a β-galactoside-bi...

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Veröffentlicht in:Infect Immun
Hauptverfasser: Elmwall, Jonas, Kwiecinski, Jakub, Na, Manli, Ali, Abukar Ahmed, Osla, Veronica, Shaw, Lindsey N., Wang, Wanzhong, Sävman, Karin, Josefsson, Elisabet, Bylund, Johan, Jin, Tao, Welin, Amanda, Karlsson, Anna
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478954/
https://ncbi.nlm.nih.gov/pubmed/28438975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00177-17
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