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5-hydroxytryptophan, a major product of tryptophan degradation, is essential for optimal replication of human parainfluenza virus

Interferon (IFN) exerts its antiviral effect by inducing a large family of cellular genes, named interferon (IFN)-stimulated genes (ISGs). An intriguing member of this family is indoleamine 2,3-dioxygenase (IDO), which catalyzes the first and rate-limiting step of the main branch of tryptophan (Trp)...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Rabbani, M A G, Barik, Sailen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478882/
https://ncbi.nlm.nih.gov/pubmed/28113063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2017.01.007
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