Erythropoietin signaling regulates heme biosynthesis

Heme is required for survival of all cells, and in most eukaryotes, is produced through a series of eight enzymatic reactions. Although heme production is critical for many cellular processes, how it is coupled to cellular differentiation is unknown. Here, using zebrafish, murine, and human models,...

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發表在:eLife
Main Authors: Chung, Jacky, Wittig, Johannes G, Ghamari, Alireza, Maeda, Manami, Dailey, Tamara A, Bergonia, Hector, Kafina, Martin D, Coughlin, Emma E, Minogue, Catherine E, Hebert, Alexander S, Li, Liangtao, Kaplan, Jerry, Lodish, Harvey F, Bauer, Daniel E, Orkin, Stuart H, Cantor, Alan B, Maeda, Takahiro, Phillips, John D, Coon, Joshua J, Pagliarini, David J, Dailey, Harry A, Paw, Barry H
格式: Artigo
語言:Inglês
出版: eLife Sciences Publications, Ltd 2017
主題:
Developmental Biology and Stem Cells
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478267/
https://ncbi.nlm.nih.gov/pubmed/28553927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24767
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