The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

Despite being overexpressed in different tumor entities, RIO kinases are hardly characterized in mammalian cells. We investigated the role of these atypical kinases in different cancer cells. Using isogenic colon-, breast- and lung cancer cell lines, we demonstrate that knockdown of RIOK1, but not o...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Weinberg, Florian, Reischmann, Nadine, Fauth, Lisa, Taromi, Sanaz, Mastroianni, Justin, Köhler, Martin, Halbach, Sebastian, Becker, Andrea C., Deng, Niantao, Schmitz, Tatjana, Uhl, Franziska Maria, Herbener, Nicola, Riedel, Bianca, Beier, Fabian, Swarbrick, Alexander, Lassmann, Silke, Dengjel, Jörn, Zeiser, Robert, Brummer, Tilman
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478185/
https://ncbi.nlm.nih.gov/pubmed/28499923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.04.015
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