Multifunctional Telodendrimer Nanocarriers Restore Synergy of Bortezomib and Doxorubicin in Ovarian Cancer Treatment

We have developed multifunctional nanoparticles (NP) for co-delivery of bortezomib (BTZ) and doxorubicin (DOX) to synchronize their pharmacokinetic profiles and synergize their activities in solid tumor treatment, a need still unmet in the clinic. Micellar NP was formed by a spatially segregated, li...

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Vydáno v:Cancer Res
Hlavní autoři: Wang, Lili, Shi, Changying, Wright, Forrest A., Guo, Dandan, Wang, Xu, Wang, Dongliang, Wojcikiewicz, Richard J.H., Luo, Juntao
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478165/
https://ncbi.nlm.nih.gov/pubmed/28396359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-16-3119
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