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Selective cyclooxygenase inhibition by SC-560 improves hepatopulmonary syndrome in cirrhotic rats

OBJECTIVE: Hepatopulmonary syndrome (HPS) is characterized by hypoxia in patients with chronic liver disease. The mechanism of HPS includes pulmonary vasodilatation, inflammation, and angiogenesis. Prostaglandins synthesized by cyclooxygenases (COX) participate in vascular responsiveness, inflammati...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chang, Ching-Chih, Lee, Wen-Shin, Hsieh, Hsian-Guey, Chuang, Chiao-Lin, Huang, Hui-Chun, Lee, Fa-Yauh, Lee, Shou-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5478154/
https://ncbi.nlm.nih.gov/pubmed/28632747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179809
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