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Heparan 2-O-sulfotransferase, hst-2, is essential for normal cell migration in Caenorhabditis elegans

The importance of heparan sulfate proteoglycans has been highlighted by a number of human genetic disorders associated with mutations in genes encoding for heparan sulfate proteoglycan protein cores or biosynthetic enzymes required for heparan sulfate (HS) assembly. To study the functional role of H...

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Autores principales: Kinnunen, Tarja, Huang, Zebo, Townsend, Joanne, Gatdula, Michelle M., Brown, Jillian R., Esko, Jeffrey D., Turnbull, Jeremy E.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC547812/
https://ncbi.nlm.nih.gov/pubmed/15671174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401591102
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