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DOT1L inhibitor improves early development of porcine somatic cell nuclear transfer embryos
Incomplete epigenetic reprogramming of the genome of donor cells causes poor early and full-term developmental efficiency of somatic cell nuclear transfer (SCNT) embryos. Previous research indicate that inhibition of the histone H3 K79 methyltransferase DOT1L, using a selective pharmacological inhib...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5478106/ https://ncbi.nlm.nih.gov/pubmed/28632762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0179436 |
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