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Mutation Location on the RAS Oncogene Affects Pathologic Features and Survival After Resection of Colorectal Liver Metastases

BACKGROUND: In the past 3 decades, a better understanding of gene mutations and their role in carcinogenesis has led to improvement in our ability to treat patients with metastatic disease. The objective of the current study was to determine whether the location of a driver mutation within an affect...

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Detalhes bibliográficos
Publicado no:Cancer
Main Authors: Frankel, Timothy L., Vakiani, Efsevia, Nathan, Hari, DeMatteo, Ronald P., Kingham, T. Peter, Allen, Peter J., Jarnagin, William R., Kemeny, Nancy E., Solit, David B., D’Angelica, Michael I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477980/
https://ncbi.nlm.nih.gov/pubmed/27737491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30351
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