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Reassociation with beta 2-microglobulin is necessary for Kb class I major histocompatibility complex binding of exogenous peptides.

T lymphocytes recognize endogenously produced antigenic peptides in association with major histocompatibility complex (MHC)-encoded molecules. Peptides from the extracellular fluid can be displayed in association with class I and class II MHC molecules. Here we report that mature Kb class I MHC mole...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Rock, K L, Rothstein, L E, Gamble, S R, Benacerraf, B
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54778/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2217182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7517
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