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Aromatic–Aromatic Interactions Enable α-Helix to β-Sheet Transition of Peptides to Form Supramolecular Hydrogels

[Image: see text] Isolated short peptides usually are unable to maintain their original secondary structures due to the lack of the restriction from proteins. Here we show that two complementary pentapeptides from a β-sheet motif of a protein, being connected to an aromatic motif (i.e., pyrene) at t...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Li, Jie, Du, Xuewen, Hashim, Saqib, Shy, Adrianna, Xu, Bing
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2016
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477776/
https://ncbi.nlm.nih.gov/pubmed/27997165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b11512
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