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Inhibition of MMP-2 and MMP-9 decreases cellular migration, and angiogenesis in in vitro models of retinoblastoma

BACKGROUND: Retinoblastoma (Rb) is the most common primary intraocular tumor in children. Local treatment of the intraocular disease is usually effective if diagnosed early; however advanced Rb can metastasize through routes that involve invasion of the choroid, sclera and optic nerve or more broadl...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:BMC Cancer
Päätekijät: Webb, Anderson H., Gao, Bradley T., Goldsmith, Zachary K., Irvine, Andrew S., Saleh, Nabil, Lee, Ryan P., Lendermon, Justin B., Bheemreddy, Rajini, Zhang, Qiuhua, Brennan, Rachel C., Johnson, Dianna, Steinle, Jena J., Wilson, Matthew W., Morales-Tirado, Vanessa M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477686/
https://ncbi.nlm.nih.gov/pubmed/28633655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-017-3418-y
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