Silencing NKG2D ligand-targeting miRNAs enhances natural killer cell-mediated cytotoxicity in breast cancer

NKG2D is one of the major activating receptors of natural killer (NK) cells and binds to several ligands (NKG2DLs). NKG2DLs are expressed on malignant cells and sensitize them to early elimination by cytotoxic lymphocytes. We investigated the clinical importance of NKG2DLs and the mechanism of NKG2D...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Shen, Jiaying, Pan, Jie, Du, Chengyong, Si, Wengong, Yao, Minya, Xu, Liang, Zheng, Huilin, Xu, Mingjie, Chen, Danni, Wang, Shu, Fu, Peifen, Fan, Weimin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477582/
https://ncbi.nlm.nih.gov/pubmed/28383557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.158
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