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Effect of Uric Acid Lowering on Renin-Angiotensin-System Activation and Ambulatory BP: A Randomized Controlled Trial

BACKGROUND AND OBJECTIVES: Higher serum uric acid levels, even within the reference range, are strongly associated with increased activity of the renin-angiotensin system (RAS) and risk of incident hypertension. However, the effect of lowering serum uric acid on RAS activity in humans is unknown, al...

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Detalles Bibliográficos
Publicado en:Clin J Am Soc Nephrol
Main Authors: McMullan, Ciaran J., Borgi, Lea, Fisher, Naomi, Curhan, Gary, Forman, John
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Nephrology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477221/
https://ncbi.nlm.nih.gov/pubmed/28320765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2215/CJN.10771016
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