Determinants of the B-cell response against a transgenic autoantigen.
The failure to induce self-tolerance of simian virus 40 large tumor antigen (T antigen) expressed in the pancreatic beta cells of transgenic mice results in an autoimmune response against this protein and the cells that synthesize it. In every transgenic mouse with delayed onset of T-antigen express...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54772/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2217180/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7487 |
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