Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases

BACKGROUND: Lymphatic metastasis is one of the leading causes of death in patients with different types of cancer and is the main prognostic factor for the disease survival. The formation of new lymphatic vessels (lymphangiogenesis) in primary tumors facilitates tumor cell dissemination to regional...

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Dades bibliogràfiques
Publicat a:J Hematol Oncol
Autors principals: García-Caballero, Melissa, Paupert, Jenny, Blacher, Silvia, Van de Velde, Maureen, Quesada, Ana Rodríguez, Medina, Miguel Angel, Noël, Agnès
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477162/
https://ncbi.nlm.nih.gov/pubmed/28629427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-017-0484-1
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