Adeno-Associated Viral Vector-Mediated mTOR Inhibition by Short Hairpin RNA Suppresses Laser-Induced Choroidal Neovascularization

Choroidal neovascularization (CNV) is the defining characteristic feature of the wet subtype of age-related macular degeneration (AMD) and may result in irreversible blindness. Based on anti-vascular endothelial growth factor (anti-VEGF), the current therapeutic approaches to CNV are fraught with di...

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Bibliografiska uppgifter
I publikationen:Mol Ther Nucleic Acids
Huvudupphovsmän: Park, Tae Kwann, Lee, Si Hyung, Choi, Jun Sub, Nah, Seung Kwan, Kim, Hee Jong, Park, Ha Yan, Lee, Heuiran, Lee, Steven Hyun Seung, Park, Keerang
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Gene & Cell Therapy 2017
Ämnen:
Original Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477068/
https://ncbi.nlm.nih.gov/pubmed/28918027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.05.012
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