Chromatin-remodelling factor Brg1 regulates myocardial proliferation and regeneration in zebrafish

The zebrafish possesses a remarkable capacity of adult heart regeneration, but the underlying mechanisms are not well understood. Here we report that chromatin remodelling factor Brg1 is essential for adult heart regeneration. Brg1 mRNA and protein are induced during heart regeneration. Transgenic o...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Xiao, Chenglu, Gao, Lu, Hou, Yu, Xu, Congfei, Chang, Nannan, Wang, Fang, Hu, Keping, He, Aibin, Luo, Ying, Wang, Jun, Peng, Jinrong, Tang, Fuchou, Zhu, Xiaojun, Xiong, Jing-Wei
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476829/
https://ncbi.nlm.nih.gov/pubmed/27929112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13787
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