Serum levels of IGF-1 and IGF-BP3 are associated with event-free survival in adult Ewing sarcoma patients treated with chemotherapy

BACKGROUND: Activation of the insulin-like growth factor 1 (IGF-1) pathway is involved in cell growth and proliferation and is associated with tumorigenesis, tumor progression, and therapy resistance in solid tumors. We examined whether variability in serum levels of IGF-1, IGF-2, and IGF-binding pr...

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Publicado en:Onco Targets Ther
Autores principales: de Groot, Stefanie, Gelderblom, Hans, Fiocco, Marta, Bovée, Judith VMG, van der Hoeven, Jacobus JM, Pijl, Hanno, Kroep, Judith R
Formato: Artigo
Lenguaje:Inglês
Publicado: Dove Medical Press 2017
Materias:
Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476720/
https://ncbi.nlm.nih.gov/pubmed/28652778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S123726
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