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Pro-invasive stimuli and the interacting protein Hsp70 favour the route of alpha-enolase to the cell surface

Cell surface expression of alpha-enolase, a glycolytic enzyme displaying moonlighting activities, has been shown to contribute to the motility and invasiveness of cancer cells through the protein non-enzymatic function of binding plasminogen and enhancing plasmin formation. Although a few recent rec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Perconti, Giovanni, Maranto, Cristina, Romancino, Daniele P., Rubino, Patrizia, Feo, Salvatore, Bongiovanni, Antonella, Giallongo, Agata
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476664/
https://ncbi.nlm.nih.gov/pubmed/28630480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04185-8
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