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Overcoming evolved resistance to population-suppressing homing-based gene drives

The recent development of a CRISPR-Cas9-based homing system for the suppression of Anopheles gambiae is encouraging; however, with current designs, the slow emergence of homing-resistant alleles is expected to result in suppressed populations rapidly rebounding, as homing-resistant alleles have a si...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Marshall, John M., Buchman, Anna, Sánchez C., Héctor M., Akbari, Omar S.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476637/
https://ncbi.nlm.nih.gov/pubmed/28630470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-02744-7
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