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Progesterone prevents epithelial-mesenchymal transition of ovine amniotic epithelial cells and enhances their immunomodulatory properties
The in vitro expansion is detrimental to therapeutic applications of amniotic epithelial cells (AEC), an emerging source of fetal stem cells. This study provides molecular evidences of progesterone (P(4)) role in preventing epithelial-mesenchymal transition (EMT) in ovine AEC (oAEC). oAEC amplified...
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| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5476612/ https://ncbi.nlm.nih.gov/pubmed/28630448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-03908-1 |
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