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The Origin of Fibrogenic Myofibroblasts in Fibrotic Liver

Liver fibrosis results from chronic liver injury of different etiologies. It is characterized by dysregulation of physiological remodeling, activation of myofibroblasts, and formation of a fibrous scar. Myofibroblasts develop contractile functions and secrete the extracellular matrix proteins that f...

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Bibliographic Details
Published in:Hepatology
Main Author: Kisseleva, Tatiana
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5476301/
https://ncbi.nlm.nih.gov/pubmed/27859502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.28948
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