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SA20. Population Pharmacokinetic Analysis and Simulations of a 2-Month Regimen for Aripiprazole Lauroxil

Background: Aripiprazole lauroxil (AL) is a prodrug of aripiprazole, formulated as an extended-release suspension approved for the treatment of schizophrenia by injection every 4 and 6 weeks. Following completion of a Phase 1 study evaluating administration of AL every 8 weeks, a pharmacokinetic (PK...

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Publicado en:Schizophr Bull
Autores principales: Hard, Marjie, Mills, Richard, Sadler, Brian, von Molke, Lisa
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475906/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx023.019
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