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Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions.

One of the earliest events in the response of mammalian cells to mitogens is activation of Na+/H+ exchange, which increases intracellular pH (pHin) in the absence of HCO3- or at external pH values below 7.2. The proliferative response can be blocked by preventing the pHin increase; yet, the prolifer...

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Bibliografiska uppgifter
Huvudupphovsmän: Gillies, R J, Martinez-Zaguilan, R, Martinez, G M, Serrano, R, Perona, R
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1990
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC54757/
https://ncbi.nlm.nih.gov/pubmed/2170979
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