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146. Glutamatergic Neurotransmission Modulates Cortico-Striatal Reward Networks Differentially for Treatment-Resistant and Treatment-Responsive Schizophrenia Patients: Evidence from a Multimodal fMRI and 1H-MRS Study

Background: Positive symptoms and specifically paranoid delusions in psychosis are characterized by a fundamental luck of trust. A number of studies show that dopaminergic dysfunction modulating the cortico-striatal reward network underlies psychosis. However, antipsychotic medication is not effecti...

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Publicat a:Schizophr Bull
Autors principals: Mouchlianitis, Elias, Vanes, Lucy, Fett, Anne-Kathrin, Shergill, Sukhi
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475662/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbx021.204
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