Somatostatin Receptor Expression in GH-Secreting Pituitary Adenomas Treated with Long-Acting Somatostatin Analogues in Combination with Pegvisomant

BACKGROUND: Growth hormone-secreting pituitary adenomas (somatotroph adenoma) predominantly express somatostatin receptors (SSTRs) subtypes 2 and 5. Higher SSTR2 expression on somatotroph adenomas results in a better response to somatostatin analogues (SSAs), which preferentially bind, but also down...

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Detalles Bibliográficos
Publicado en:Neuroendocrinology
Main Authors: Franck, Sanne E., Gatto, Federico, van der Lely, Aart Jan, Janssen, Joseph A.M.J.L., Dallenga, Alof H.G., Nagtegaal, A. Paul, Hofland, Leo J., Neggers, Sebastian J.C.M.M.
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2017
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475231/
https://ncbi.nlm.nih.gov/pubmed/27455094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000448429
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