TMOD-08. INVESTIGATING PEDIATRIC GBM USING IN VIVO SOMATIC MOUSE MOSAICS WITH LOCUS-SPECIFIC, STABLY-INTEGRATED TRANSGENIC ELEMENTS

Viral vectors and electroporation (EP)-mediated gene transfers are efficient means of inducing somatic mosaicism in mice, but they lack the exquisite control over transgene copy number, gene zygosity, and genomic-locus speci-ficity that genetically engineered mouse models (GEMMs) provide. Here, we d...

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Publicat a:Neuro Oncol
Autors principals: Kim, Gi Bum, Dutra-Clarke, Marina, Levy, Rachelle, Park, Hannah, Sabet, Sara, Molina, Jessica, Akhtar, Aslam Abbasi, Danielpour, Moise, Breunig, Joshua
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475186/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.207
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