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MEDU-32. ADVANCING PRECLINICAL MODELING OF HIGH RISK MEDULLOBLASTOMA BY PERFORMING CLINICALLY-RELEVANT RADIOTHERAPY ON PATIENT-DERIVED XENOGRAFTS
Medulloblastoma (MB) is the most common malignant pediatric brain tumor that comprises four major subgroups. Group 3 (MB(Grp3)) that overexpress MYC and Sonic hedgehog (MB(SHH)) with MYCN amplification and TP53 loss of function have a particularly poor prognosis. MBs are treated with surgical resect...
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| Publicado no: | Neuro Oncol |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5475156/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.182 |
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