MEDU-32. ADVANCING PRECLINICAL MODELING OF HIGH RISK MEDULLOBLASTOMA BY PERFORMING CLINICALLY-RELEVANT RADIOTHERAPY ON PATIENT-DERIVED XENOGRAFTS

Medulloblastoma (MB) is the most common malignant pediatric brain tumor that comprises four major subgroups. Group 3 (MB(Grp3)) that overexpress MYC and Sonic hedgehog (MB(SHH)) with MYCN amplification and TP53 loss of function have a particularly poor prognosis. MBs are treated with surgical resect...

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Bibliografske podrobnosti
izdano v:Neuro Oncol
Main Authors: Smith, Stephanie, Tinkle, Christopher, Bianski, Brandon, Orr, Brent, Robinson, Giles, Nimmervoll, Birgit, Morel, Victoria, Gilbertson, Richard, Gajjar, Amar, Merchant, Thomas, Roussel, Martine
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2017
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Abstracts
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475156/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.182
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