LGG-18. MOLECULAR ALTERATIONS PREDICT RESPONSE TO CHEMOTHERAPY AND OUTCOME OF PEDIATRIC LOW-GRADE GLIOMA

BACKGROUND: Pediatric low-grade glioma (pLGG) is the most common childhood brain tumor. Recently, alterations of the RAS/MAPK pathway have been identified as the major driver of PLGG however little is known about prognostic implications. DESIGN/METHODS: We undertook a large population based study of...

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Veröffentlicht in:Neuro Oncol
Hauptverfasser: Zapotocky, Michal, Ryall, Scott, Mistry, Matthew, Arnoldo, Anthony, Lassaletta, Alvaro, Stucklin, Ana Guerreiro, Krishnatry, Rahul, Fukuoka, Kohei, Dirks, Peter, Ramaswamy, Vijay, Bartels, Ute, Huang, Annie, Zhukova, Nataliya, Bouffet, Eric, Tabori, Uri, Hawkins, Cynthia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475111/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.151
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