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BIOL-06. NOVEL ONCOGENIC ROLE FOR NFIA IN GLIOMA

The Nuclear Factor I-A (NFIA) transcription factor is a glioma tumor promoter. However, the mechanism by which NFIA regulates glioma cell survival and drug resistance is still unknown. Here we report that the NFIA pro-survival effect is mediated via an NFIA-NFκB p65 feedforward loop. We examined eff...

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Udgivet i:Neuro Oncol
Main Authors: Hoxha, Edlira, Andreas, Kloetgen, Song, Hae-Ri
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475073/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.014
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