EPND-04. INVESTIGATING THE BIOLOGICAL CONSEQUENCES OF PI3K PATHWAY INHIBITION ON PAEDIATRIC EPENDYMOMA TUMOURS

INTRODUCTION: Paediatric ependymoma has a relatively poor prognosis with current therapies yielding suboptimal outcomes due to these tumours’ general chemoresistant nature. We have identified that the PI3K pathway, a cell survival signalling cascade implicated in many malignancies, was activated in...

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Опубликовано в: :Neuro Oncol
Главные авторы: Estranero, Jasper, Ascough, Caitlyn, Duane, Holly, Chapman, Rebecca, Rogers, Hazel, Grundy, Richard
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5475025/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox083.062
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