Somatostatin-IRES-Cre Mice: Between Knockout and Wild-Type?

The neuropeptide somatostatin (SOM) is widely expressed in rodent brain and somatostatin-IRES-Cre (SOM-cre) mouse strains are increasingly used to unravel the physiology of SOM-containing neurons. However, while knock-in targeting strategy greatly improves Cre-Lox system accuracy, recent reports hav...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Viollet, Cécile, Simon, Axelle, Tolle, Virginie, Labarthe, Alexandra, Grouselle, Dominique, Loe-Mie, Yann, Simonneau, Michel, Martel, Guillaume, Epelbaum, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474965/
https://ncbi.nlm.nih.gov/pubmed/28674519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00131
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