Macrophages Facilitate Electrical Conduction in the Heart

Organ-specific functions of tissue-resident macrophages in the steady-state heart are unknown. Here we show that cardiac macrophages facilitate electrical conduction through the distal atrioventricular node, where conducting cells densely intersperse with elongated macrophages expressing connexin 43...

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Published in:Cell
Main Authors: Hulsmans, Maarten, Clauss, Sebastian, Xiao, Ling, Aguirre, Aaron D., King, Kevin R., Hanley, Alan, Hucker, William J., Wülfers, Eike M., Seemann, Gunnar, Courties, Gabriel, Iwamoto, Yoshiko, Sun, Yuan, Savol, Andrej J., Sager, Hendrik B., Lavine, Kory J., Fishbein, Gregory A., Capen, Diane E., Da Silva, Nicolas, Miquerol, Lucile, Wakimoto, Hiroko, Seidman, Christine E., Seidman, Jonathan G., Sadreyev, Ruslan I., Naxerova, Kamila, Mitchell, Richard N., Brown, Dennis, Libby, Peter, Weissleder, Ralph, Swirski, Filip K., Kohl, Peter, Vinegoni, Claudio, Milan, David J., Ellinor, Patrick T., Nahrendorf, Matthias
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474950/
https://ncbi.nlm.nih.gov/pubmed/28431249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.03.050
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