Pretreatment with cyclosporine and anti-interleukin 2 receptor antibody abrogates the anti-idiotype response in rat recipients of cardiac allografts.

A 10-day course with ART-18, a mouse monoclonal antibody (mAb) directed against the rat interleukin 2 receptor (IL-2R), prolongs the survival of (LEW x BN)F1 cardiac allografts in LEW recipients to approximately 3 weeks (acute rejection = 8 days, P less than 0.001). We examined host responses agains...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Tanaka, K, Tilney, N L, Stunkel, K G, Hancock, W W, Diamantstein, T, Kupiec-Weglinski, J W
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1990
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC54749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2217171/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.19.7375
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