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AraC-like transcriptional activator CuxR binds c-di-GMP by a PilZ-like mechanism to regulate extracellular polysaccharide production

Cyclic dimeric GMP (c-di-GMP) has emerged as a key regulatory player in the transition between planktonic and sedentary biofilm-associated bacterial lifestyles. It controls a multitude of processes including production of extracellular polysaccharides (EPSs). The PilZ domain, consisting of an N-term...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Schäper, Simon, Steinchen, Wieland, Krol, Elizaveta, Altegoer, Florian, Skotnicka, Dorota, Søgaard-Andersen, Lotte, Bange, Gert, Becker, Anke
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474780/
https://ncbi.nlm.nih.gov/pubmed/28559336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1702435114
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